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Invitrogen
SBF1 Polyclonal Antibody
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产品信息
PA5-66780
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human SBF1
偶联物
形式
Liquid
浓度
0.2 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: LRSCTFQLLKM AFDEEVGSDS AELFRKQLHK LRYPPDIRAT FAFTLGSAHT PGRPPRVTKD KGPSLRTLSR NLVKNAKKTI GRQHVTRKKY N
Highest antigen sequence identity to the following orthologs - mouse 97%, rat 97%.
靶标信息
Probable pseudophosphatase. Lacks several amino acids in the catalytic pocket which renders it catalytically inactive as a phosphatase. The pocket is however sufficiently preserved to bind phosphorylated substrates, and maybe protect them from phosphatases. Inhibits myoblast differentiation in vitro and induces oncogenic transformation in fibroblasts. According to PubMed:20937701, may function as a guanine nucleotide exchange factor (GEF) activating RAB28. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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