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Proteintech
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Immunogen sequence: LLEDKGLAE VSKVAEQVLN AVNKGLYREA TELWGKAEMI IEQNTDGVNF YNILTKSTPT STMESSLEFT QSHLVCLCQR HVRHLQRDAL SQLMNGPIRK KLKIIPEDQS WGGQATNVFV NMEEDFMKPV ISIVDELLEA GINVTVYNGQ LDLIVDTMGQ EAWVRKLKWP ELPKFSQLKW KALYSDPKSL ETSAFVKSYK NLAFYWILKA GHMVPSDQGD MALKMMRLVT QQE
The RNA-induced silencing complex (RISC) is a key player in the regulation of gene expression through RNA interference (RNAi) mechanisms. It operates by utilizing small RNA molecules-such as microRNAs (miRNAs), small interfering RNAs (siRNAs), and PIWI-interacting RNAs (piRNAs)-which are processed from double-stranded RNA precursors by enzymes like Drosha and Dicer in animals, and DICER-LIKE in plants. RISC is a versatile molecular complex consisting of Argonaute proteins as its core component, which guides the complex to the target RNA by complementary base pairing. Once assembled, RISC can recruit other proteins that mediate gene silencing by degrading or inhibiting the translation of the target RNA. This post-transcriptional regulation system is integral to numerous biological processes, allowing cells to control gene expression finely and respond to endogenous and exogenous signals. The functionality of RISC in gene silencing highlights its significance in the broader context of genetic regulation and has implications in therapies that target gene expression through RNAi.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: retinoid inducible serine carboxypeptidase; Retinoid-inducible serine carboxypeptidase; Serine carboxypeptidase 1; serine carboxypeptidase 1 precursor protein
基因别名: HSCP1; MSTP034; RISC; SCP1; SCPEP1; UNQ265/PRO302
UniProt ID: (Human) Q9HB40
Entrez Gene ID: (Human) 59342