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Invitrogen
SDHAF3 Polyclonal Antibody
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SDHAF3 Antibody (PA5-24526) in IHC (P)
Immunohistochemistry analysis of ACN9 in formalin fixed and paraffin embedded human hepatocarcinoma. Samples were incubated with ACN9 polyclonal antibody (Product # PA5-24526) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
产品信息
PA5-24526
产品规格
种属反应
Human,
Mouse
已发表种属
Zebrafish
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human ACN9
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: ACN9 homolog; protein ACN9 homolog, mitochondrial; SDH assembly factor 3; Succinate dehydrogenase assembly factor 3, mitochondrial
基因别名: 0610005M07Rik; 4933430A16Rik; ACN9; DC11; LYRM10; Sdh7; SDHAF3
UniProt ID: (Human) Q9NRP4, (Mouse) Q8BQU3
Entrez Gene ID: (Human) 57001, (Mouse) 71238
