Search
NeoBiotechnologies
SDHB (Succinate Dehydrogenase B) (Pheochromocytoma Marker) Recombinant Mouse Monoclonal Antibody (rSDHB/6948)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
图: 1 / 1
SDHB (Succinate Dehydrogenase B) (Pheochromocytoma Marker) Antibody (6390-MSM8-P1ABX) in IHC (P)
Formalin-fixed, paraffin-embedded human hepatocellular carcinoma stained with SDHB Recombinant Mouse Monoclonal Antibody (rSDHB/6948). HIER: Tris/EDTA, pH9.0, 45 min. 2°C: HRP-polymer, 30 min. DAB, 5 min.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
6390-MSM8-P1ABX
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
rSDHB/6948
抗原
Recombinant fragment (around aa180-280) of human SDHB protein.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A/G
保存液
PBS
内含物
no preservative
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Positive Control:Jurkat or HepG2 cells. Human kidney or heart tissue.
Cellular Location: Cytoplasm. Mitochondria.
靶标信息
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: FLJ92337; iron-sulfur subunit; iron-sulfur subunit of complex II; malate dehydrogenase [quinone] iron-sulfur subunit; OTTHUMP00000044624; succinate dehydrogenase complex, subunit B, iron sulfur (Ip); succinate-ubiquinone oxidoreductase Ip subunit precursor; unnamed protein product
基因别名: CWS2; IP; MC2DN4; PGL4; PPGL4; SDH; SDH1; SDH2; SDHIP
UniProt ID: (Human) P21912
Entrez Gene ID: (Human) 6390
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
