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Invitrogen
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PA1-31455 detects SEC61A1 from human samples.
PA1-31455 has been successfully used in Western blot applications.
The PA1-31455 immunogen is: Peptide with sequence KEQSEVGSMGALLF, from C-Terminus of the protein sequence according to NP_037468
The Sec61 complex is responsible for translocation of proteins across the rough endoplasmic reticulum membrane. Sec61 is composed of three subunits: alpha, beta, and gamma; that associate to form a heterotrimer. Multiple heterotrimers associate forming the ER translocon. Sec61 alpha is a polytopic protein that has ten membrane-spanning loops. Sec61 has been found to be tightly associated with membrane bound ribosomes, either directly or through adaptor proteins, and is required for assembly of membrane and secretory proteins.
仅用于科研。不用于诊断过程。未经明确授权不得转售。