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Proteintech
SEMA4F Polyclonal Antibody
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产品信息
12474-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SEMA4F Fusion Protein Ag3082 (272-615 aa encoded by BC018361)
偶联物
形式
Liquid
浓度
0.27 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: LVTTDTAYL RVVAHRVTSL SGKEYDVLYL GTEDGHLHRA VRIGAQLSVL EDLALFPEPQ PVENMKLYHS WLLVGSRTEV TQVNTTNCGR LQSCSECILA QDPVCAWSFR LDECVAHAGE HRGLVQDIES ADVSSLCPKE PGERPVVFEV PVATAAHVVL PCSPSSAWAS CVWHQPSGVT ALTPRRDGLE VVVTPGAMGA YACECQEGGA AHVVAAYSLV WGSQRDAPSR AHTVGAGLAG FFLGILAASL TLILIGRRQQ RRRQRELLAR DKVGLDLGAP PSGTTSYSQD PPSPSPEDER LPLALAKRGS GFGGFSPPFL LDPCPSPAHI RLTGAPLATC DETSI (272-615 aa encoded by BC018361)
靶标信息
SEMA4F has growth cone collapse activity against retinal ganglion-cell axons.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: sema domain immunoglobulin domain transmembrane domain (TM) and short cytoplasmic domain (semaphorin) 4F; sema domain, immunoglobulin domain (Ig), TM domain, and short cy; sema domain, immunoglobulin domain (Ig), TM domain, and short cytoplasmic domain; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F; Sema M; Sema W; semaphorin 4f; semaphorin M; Semaphorin-4F; Semaphorin-M; Semaphorin-W
基因别名: M-SEMA; m-Sema-M; PRO2353; S4F; Sema W; SEMA4F; SEMAM; SEMAW
UniProt ID: (Human) O95754, (Rat) Q9Z143, (Mouse) Q9Z123
Entrez Gene ID: (Human) 10505, (Rat) 29745, (Mouse) 20355
neural crest cell migration
cell-cell signaling
nervous system development
axon guidance
positive regulation of cell migration
retinal ganglion cell axon guidance
negative regulation of axon extension involved in axon guidance
negative chemotaxis
semaphorin-plexin signaling pathway
negative regulation of axon extension
