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The antibody detects a 120kDa* protein corresponding to the apparent molecular mass of Sema-6A on SDS-PAGE immunoblots of Sema-6A transfected COS7 cells, human colorectal cancer cells, and rat PC12 cells. In addition, shRNA knockdown of Sema-6A expression significantly reduces detection of Sema-6A using anti-Sema-6A (a.a. 772-787) antibody.
SEMA6A can act as repulsive axon guidance cues. It may play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Mutant line 997; Sema Q; Sema VIA; SEMA6A-1; semaphorin 6A-1; Semaphorin Q; Semaphorin VIA; Semaphorin-6A; Semaphorin-6A-1
基因别名: 9330158E07; A730020P05Rik; AI851735; b2b997Clo; KIAA1368; SEMA6A; Sema6A-1; SEMAQ; VIa
UniProt ID: (Mouse) O35464
Entrez Gene ID: (Rat) 361324, (Mouse) 20358