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Invitrogen
SEMA6A Monoclonal Antibody (201932)
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产品信息
MA5-61011
产品规格
种属反应
Mouse
宿主/亚型
Rat
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
201932
抗原
S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse Semaphorin 6A, Gly19-Thr649
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
0.5 mg/mL
规格
500 µg
纯化类型
Protein A/G
保存液
PBS with trehalose
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute at 0.5 mg/mL in sterile PBS.
靶标信息
SEMA6A can act as repulsive axon guidance cues. It may play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Mutant line 997; sema Q; sema VIA; semaphorin Q; semaphorin VIA; semaphorin-6A-1; unnamed protein product
基因别名: A730020P05Rik; Sema6A-1; Semaq; VIa
UniProt ID: (Mouse) O35464
Entrez Gene ID: (Mouse) 20358
neural crest cell migration
neuron migration
apoptotic process
cell surface receptor signaling pathway
axon guidance
negative regulation of angiogenesis
cellular response to vascular endothelial growth factor stimulus
negative chemotaxis
centrosome localization
negative regulation of ERK1 and ERK2 cascade
semaphorin-plexin signaling pathway
negative regulation of cell adhesion involved in sprouting angiogenesis
negative regulation of vascular endothelial growth factor signaling pathway
negative regulation of sprouting angiogenesis
positive regulation of neuron migration
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