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Invitrogen
SEMA7A Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-50753
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to a region derived from internal residues of human semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody detects endogenous levels of total CD108 / SEMA7A protein.
靶标信息
CD108 (Sema7A) is a GPI-anchored semaphorin family member, which enhances central and peripheral axonal growth and is required for proper axon track formation during ebryogenesis. CD108 also regulates osteoclast differentiation and pre-osteoblastic cell migration, and in immune system affects cell proliferation, chemotaxis and cytokine release. On erythrocytes CD108 defines the JMH (John-Milton-Hagen) human blood group. CD108 signalizes through its receptors - plexin C1 and beta1 integrins.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD108; CDw108; H-Sema K1; JMH blood group antigen; John-Milton-Hargen human blood group Ag; MGC126692; MGC126696; Sema K1; Sema L; Semaphorin K1; Semaphorin-7A; Semaphorin-K1; Semaphorin-L
基因别名: 2900057C09Rik; CD108; CDw108; H-Sema-L; M-Sema-L; SEMA7A; SEMAL; Semk1
UniProt ID: (Mouse) Q9QUR8
Entrez Gene ID: (Mouse) 20361
osteoblast differentiation
positive regulation of protein phosphorylation
inflammatory response
integrin-mediated signaling pathway
multicellular organism development
nervous system development
olfactory lobe development
cell differentiation
neuron projection development
positive regulation of axon extension
axon extension
regulation of inflammatory response
positive regulation of macrophage cytokine production
positive regulation of ERK1 and ERK2 cascade
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