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Abnova
SENP2 Polyclonal Antibody, MaxPab™
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产品信息
H00059343-B02P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SENP2 (NP_067640.2, 1 a.a. approximately 589 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MYRWLVRILG TIFRFCDRSV PPARALLKRR RSDSTLFSTV DTDEIPAKRP RLDCFIHQVK NSLYNAASLF GFPFQLTTKP MVTSACNGTR NVAPSGEVFS NSSSCELTGS GSWNNMLKLG NKSPNGISDY PKIRVTVTRD QPRRVLPSFG FTLNSEGCNR RPGGRRHSKG NPESSLMWKP QEQAVTEMIS EESGKGLRRP HCTVEEGVQK EEREKYRKLL ERLKESGHGN SVCPVTSNYH SSQRSQMDTL KTKGWGEEQN HGVKTTQFVP KQYRLVETRG PLCSLRSEKR CSKGKITDTE TMVGIRFENE SRRGYQLEPD LSEEVSARLR LGSGSNGLLR RKVSIIETKE KNCSGKERDR RTDDLLELTE DMEKEISNAL GHGPQDEILS SAFKLRITRG DIQTLKNYHW LNDEVINFYM NLLVERNKKQ GYPALHVFST FFYPKLKSGG YQAVKRWTKG VNLFEQEIIL VPIHRKVHWS LVVIDLRKKC LKYLDSMGQK GHRICEILLQ YLQDESKTKR NSDLNLLEWT HHSMKPHEIP QQLNGSDCGM FTCKYADYIS RDKPITFTQH QMPLFRKKMV WEILHQQLL
靶标信息
SUMO is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1, SUMO2, and SUMO3 into the conjugatable mature forms and catalyze the deconjugation of these same SUMO proteins from their targeted substrates. SENP2 may also down-regulate CTNNB1 levels and thereby modulate the Wnt pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Axam2; CT; Sentrin-specific protease 2; Sentrin/SUMO-specific protease SENP2; SMT3-specific isopeptidase 2; Smt3ip2; SUMO1/sentrin/SMT3 specific protease 2
基因别名: AXAM2; KIAA1331; SENP2; SMT3IP2
UniProt ID: (Human) Q9HC62
Entrez Gene ID: (Human) 59343
positive regulation of protein phosphorylation
heart development
dorsal/ventral axis specification
protein transport
Wnt signaling pathway
protein sumoylation
protein desumoylation
regulation of Wnt signaling pathway
negative regulation of protein ubiquitination
positive regulation of protein ubiquitination
protein destabilization
negative regulation of protein binding
regulation of DNA endoreduplication
negative regulation of chromatin binding
negative regulation of DNA damage response, signal transduction by p53 class mediator
fat cell differentiation
positive regulation of transcription from RNA polymerase II promoter
mRNA transport
trophoblast giant cell differentiation
labyrinthine layer development
spongiotrophoblast layer development
regulation of G1/S transition of mitotic cell cycle
