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Invitrogen
SERCA3 ATPase Polyclonal Antibody
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SERCA3 ATPase Antibody (PA1-910A) in IHC
Molecular vision 2007 -
Figure 6 Molecular markers of endoplasmic reticulum (ER) reveal distinct retinal distribution and lamination patterns. A - D : Confocal image of retina triple labeled for calreticulin, COX IV and PNA. Scale bar equal 20 mum. A : Retina stained for calreticulin, a Ca 2+ -binding protein present in all ER lumen. Note the intense labeling in the IS, OPL and INL. B : Location of calreticulin (red) and COX ... View More
产品信息
PA1-910A
产品规格
已发表种属
Dog,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic Peptide: V(29) T D A R E R Y G P N(39).
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
产品详细信息
PA1-910A detects sarcoplasmic or endoplasmic reticulum calcium ATPase 3 (SERCA3) mouse and rat samples. This antibody does not detect other SERCA isoforms.
PA1-910A has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~97 kDa protein representing recombinant SERCA3 from rat samples.
PA1-910A immunizing peptide corresponds to amino acid residues 29-39 from rat and mouse SERCA3. PA1-910A immunizing peptide (Cat. # PEP-015) is available for neutralization and control experiments.
靶标信息
ATP dependent calcium pumps are responsible in part for the maintenance of low cytoplasmic free calcium concentrations. The ATP pumps that reside in intracellular organelles are encoded by a family of structurally related enzymes, termed the sarcoplasmic or endoplasmic reticulum calcium ATPases (SERCA). The SERCA2 gene is subject to tissue dependent processing which is responsible for the generation of SERCA2a muscle-specific isoform expressed in type I (slow) skeletal, cardiac and smooth muscle and the SERCA2b isoform expressed in all cell types. SERCA3 has been found to co-express with SERCA2b in platelets, mast cells, lymphoid cells, and epithelial cells. Due to this pattern of expression it is referred to as the non-muscle form of SERCA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
