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Proteintech
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Immunogen sequence: DNIFIAPVG ISTAMGMISL GLKGETHEQV HSILHFKDFV NASSKYEITT IHNLFRKLTH RLFRRNFGYT LRSVNDLYIQ KQFPILLDFK TKVREYYFAE AQIADFSDPA FISKTNNHIM KLTKGLIKDA LENIDPATQM MILNCIYFKG SWVNKFPVEM THNHNFRLNE REVVKVSMMQ TKGNFLAAND QELDCDILQL EYVGGISMLI VVPHKMSGMK TLEAQLTPGV VERWQKSMTN RTREVLLPKF KLEKNYNLVE SLKLMGIRML FDKNGNMAGI SDQRIAIDLF KHQGTITVNE EGTQATTVTT VGFMPLSTQV RFTVDRPFLF LIYEHRTSCL LFMGRVANPS RS (149-499 aa encoded by BC035028)
The product encoded by this gene is a serine proteinase inhibitor which rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. The gene contains five exons and four introns. This protein shares homology with antithrombin III and other members of the alpha 1-antitrypsin superfamily. Mutations in this gene are associated with heparin cofactor II deficiency.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: HC-II; Heparin cofactor 2; Heparin cofactor II; HLS2; leuserpin 2; leuserpin-2; Protease inhibitor leuserpin-2; serine (or cysteine) peptidase inhibitor, clade D, member 1; serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1; serine (or cysteine) proteinase inhibitor, clade D, member 1; Serpin D1; serpin peptidase inhibitor, clade D (heparin cofactor), member 1
基因别名: AA985900; AI303446; D22S673; HC2; HCF2; HCII; HLS2; LS2; rls2var1; SERPIND1; THPH10
UniProt ID: (Human) P05546, (Rat) Q64268, (Mouse) P49182
Entrez Gene ID: (Human) 3053, (Rat) 79224, (Mouse) 15160