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Invitrogen
SESTD1 Polyclonal Antibody
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产品信息
PA5-65240
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human SESTD1
偶联物
形式
Liquid
浓度
0.1 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: PQVMKLLDSLR EQYTRYQEVC RQRSKRTQLE EIQQKVMQVV NWLEGPGSEQ LRAQWGIGDS IRASQALQQK HEEIESQHSE WFAVYVEL
Highest antigen sequence identity to the following orthologs - mouse 100%, rat 100%.
靶标信息
SESTD1 was initially identified in mutant zebrafish with defects in the spontaneous contraction and touch response as a novel gene, solo, encoding a protein containing SEC14 and spectrin repeat domains. Other experiments indicated that SESTD1 interacts with the TRPC4 and TRPC5, members of the transient receptor potential channel family, via the TRPC calmodulin- and inositol 1, 4, 5-triphosphate receptor-binding domain and is essential for efficient receptor-mediated activation of TRPC5, suggesting that SESTD1 is a novel regulator of these TRPC proteins.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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