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Abnova
SF3B2 Polyclonal Antibody, MaxPab™
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产品信息
H00010992-B01P
产品规格
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SF3B2 (AAH07610.1, 1 a.a. approximately 636 a.a) full-length human protein.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
See Label
规格
50 µg
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MDDPSVGPKI PQALEKILQL KESRQEEMNS QQEEEEMETD ARSSLGQSAS ETEEDTVSVS KKEKNRKRRN RKKKKKPQRV RGVSSESSGD REKDSTRSRG SDSPAADVEI EYVTEEPEIY EPNFIFFKRI FEAFKLTDDV KKEKEKEPEK LDKLENSAAP KKKGFEEEHK DSDDDSSDDE QEKKPEAPKL SKKKLRRMNR FTVAELKQLV ARPDVVEMHD VTAQDPKLLV HLKATRNSVP VPRHWCFKRK YLQGKRGIEK PPFELPDFIK RTGIQEMREA LQEKEEQKTM KSKMREKVRP KMGKIDIDYQ KLHDAFFKWQ TKPKLTIHGD LYYEGKEFET RLKEKKPGDL SDELRISLGM PVGPNAHKVP PPWLIAMQRY GPPPSYPNLK IPGLNSPIPE SCSFGYHAGG WGKPPVDETG KPLYGDVFGT NAAEFQTKTE EEEIDRTPWG ELEPSDEESS EEEEEEESDE DKPDETGFIT PADSGLITPG GFSSVPAGME TPELIELRKK KIEEAMDGSE TPQLFTVLPE KRTATVGGAM MGSTHIYDMS TVMSRKGPAP ELQGVEVALA PEELELDPMA MTQKYEEHVR EQQAQVEKED FSDMVAEHAA KQKQKKRKAQ PQDSRGGSKK YKEFKF
靶标信息
Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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