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OriGene
SFRP2 Monoclonal Antibody (OTI6C2), TrueMAB™
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
CF807497
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
OTI6C2
抗原
Human recombinant protein fragment corresponding to amino acids 25-295 of human SFRP2 produced in E.coli.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 8% trehalose
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
靶标信息
This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FRP 2; MGC128911; MGC153618; MGC53344; SARP 1; SARP-1; SDF 5; secreted apoptosis related protein 1; sFRP 2; sFRP-2; Sfrp2 protein; similar to frizzled-like receptor CRD; testicular tissue protein Li 170; unnamed protein product
基因别名: FRP-2; SARP1; SDF-5
UniProt ID: (Human) Q96HF1
Entrez Gene ID: (Human) 6423
regulation of cell growth
patterning of blood vessels
outflow tract morphogenesis
cardiac left ventricle morphogenesis
cell-cell signaling
response to nutrient
positive regulation of cell proliferation
negative regulation of cell proliferation
response to xenobiotic stimulus
negative regulation of gene expression
negative regulation of epithelial to mesenchymal transition
regulation of neuron projection development
regulation of Wnt signaling pathway
negative regulation of Wnt signaling pathway
positive regulation of cell growth
negative regulation of cell growth
negative regulation of cell migration
positive regulation of cell adhesion mediated by integrin
non-canonical Wnt signaling pathway
regulation of apoptotic process
positive regulation of apoptotic process
positive regulation of fat cell differentiation
positive regulation of angiogenesis
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of epithelial cell proliferation
negative regulation of peptidyl-tyrosine phosphorylation
canonical Wnt signaling pathway
sclerotome development
negative regulation of dermatome development
hematopoietic stem cell proliferation
cellular response to X-ray
negative regulation of canonical Wnt signaling pathway
positive regulation of canonical Wnt signaling pathway
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
regulation of midbrain dopaminergic neuron differentiation
regulation of stem cell division
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