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Invitrogen
SFRS15 Polyclonal Antibody
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产品信息
PA5-53838
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: PITPPVSIPP PHTPPISIPN STIAGINEDT TKDLSIGNPI PTVVSGARGN AESGDSVKMY GSAVPPAAPT NLPTPPVTQP VSLLGTQGVA PGPVIGLQAP STGLLGARPG LIPLQRPPGM P
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 78%.
靶标信息
The family of SR factors all contain one or more RNA recognition motifs (RRM) and an SR-rich domain. They are not only essential for constitutive splicing, but also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites. Splicing factor arginine/serine-rich 15 (SFRS15), also designated CTD-binding SR-like protein RA4, contains one RRM and one SR-rich domains. SFRS15 interacts with C-terminal repetitive domain (CTD) of Pol II and is believed to functionally and physically link transcription and pre-mRNA processing. Localized to the nucleus, SFRS15 is expressed as two isoforms produced by alternative splicing.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CTD-binding SR-like protein RA4; pre-mRNA splicing SR protein rA4; SFR15; splicing factor serine alanine 15; Splicing factor, arginine/serine-rich 15; SR-like CTD-associated factor 4; SR-related and CTD-associated factor 4
基因别名: KIAA1172; SCAF4; SFRS15; SRA4
UniProt ID: (Human) Q6P1M5
Entrez Gene ID: (Human) 57466
