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Invitrogen
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Immunogen sequence: ESKMGELPLD INIQEPRWDQ STFLGRARHF FTVTDPRNLL LSGAQLEASR NIVQNYRAGV VTPGITEDQL WRAKYVYDSA FHPDTGEKVV LIGRMSAQVP MN
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 93%.
Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway (PubMed:30442778). Mitochondrial serine is converted to glycine and formate, which then exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors. Also catalyzes an electroneutral exchange of tricarboxylate, dicarboxylate, or phosphoenolpyruvate across the mitochondrial inner membrane.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Sideroflexin-3; tricarboxylate carrier; tricarboxylate carrier-like protein
基因别名: BA108L7.2; SFX3; SFXN3; TCC
UniProt ID: (Human) Q9BWM7, (Rat) Q9JHY2, (Mouse) Q91V61
Entrez Gene ID: (Human) 81855, (Rat) 65042, (Mouse) 94280