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Invitrogen
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Immunogen sequence: KEEQLPLRAG YQKTSDTIAP WFHGILTLKK ANELLLSTGM PGSFLIRVSE RIKGYALSYL SEDGCKHFLI DASADAYSFL GVDQLQHATL ADLVEYHKEE PITSLGKELL LYPCGQQ
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.
SH2D4A inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. SH2D4A may play a role in T-cell development and function.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ20967; Protein phosphatase 1 regulatory subunit 38; protein phosphatase 1, regulatory subunit 38; Protein SH(2)A; SH2 domain-containing 4A; SH2 domain-containing protein 4A
基因别名: 2210402M20Rik; PPP1R38; SH2A; SH2D4A
UniProt ID: (Human) Q9H788, (Mouse) Q9D7V1, (Rat) Q6AYC8
Entrez Gene ID: (Human) 63898, (Mouse) 72281, (Rat) 306376