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Proteintech
SH3BP5 Polyclonal Antibody
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产品信息
11127-2-AP
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SH3BP5 Fusion Protein Ag1592 (50-455 aa encoded by BC010123)
偶联物
形式
Liquid
浓度
0.23 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: EKLNQSTDD INRRETELED ARQKFRSVLV EATVKLDELV KKIGKAVEDS KPYWEARRVA RQAQLEAQKA TQDFQRATEV LRAAKETISL AEQRLLEDDK RQFDSAWQEM LNHATQRVME AEQTKTRSEL VHKETAARYN AAMGRMRQLE KKLKRAINKS KPYFELKAKY YVQLEQLKKT VDDLQAKLTL AKGEYKMALK NLEMISDEIH ERRRSSAMGP RGCGVGAEGS STSVEDLPGS KPEPDAISVA SEAFEDDSCS NFVSEDDSET QSVSSFSSGP TSPSEMPDQF PAVVRPGSLD LPSPVSLSEF GMMFPVLGPR SECSGASSPE CEVERGDRAE GAENKTSDKA NNNRGLSSSS GSGGSSKSQS STSPEGQALE NRMKQLSLQC SKGRDGIIAD IKMVQIG (50-455 aa encoded by BC010123)
靶标信息
Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: SH3 binding protein; SH3 domain-binding protein 5; SH3 domain-binding protein that preferentially associates with BTK; SH3-domain binding protein 5 (BTK-associated); SH3BP-5; Vascular endothelial cell-specific protein 18
基因别名: AI606498; SAB; SH3BP-5; SH3BP5; Vesp18
UniProt ID: (Human) O60239, (Rat) Q91Y80, (Mouse) Q9Z131
Entrez Gene ID: (Human) 9467, (Rat) 117186, (Mouse) 24056
