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Proteintech
SIGLEC5 Polyclonal Antibody
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产品信息
13230-1-AP
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SIGLEC5 Fusion Protein Ag4101 (241-442 aa encoded by BC029896)
偶联物
形式
Liquid
浓度
0.13 mg/mL
规格
19.5 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: IFRNGIALE ILQNTSYLPV LEGQALRLLC DAPSNPPAHL SWFQGSPALN ATPISNTGIL ELRRVRSAEE GGFTCRAQHP LGFLQIFLNL SVYSLPQLLG PSCSWEAEGL HCRCSFRARP APSLCWRLEE KPLEGNSSQG SFKVNSSSAG PWANSSLILH GGLSSDLKVS CKAWNIYGSQ SGSVLLLQGR SNLGTGVVPA ALG (241-442 aa encoded by BC029896)
靶标信息
SIGLEC5 (CD170) is a member of the sialic acid-binding immunoglobulin-like lectin family expressed mainly on myeloid cells such as neutrophils and monocytes. It functions as an inhibitory receptor that recognizes sialylated glycans and transduces signals through immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in its cytoplasmic tail, helping regulate innate immune responses and dampen inflammation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: CD170; CD33 antigen-like 2; OB-binding protein 2; OB-BP2; Obesity-binding protein 2; Sialic acid-binding Ig-like lectin 5; sialic acid-binding immunoglobulin-like lectin 5; Siglec-5
基因别名: CD170; CD33L2; OB-BP2; OBBP2; SIGLEC-5; SIGLEC5
UniProt ID: (Human) O15389
Entrez Gene ID: (Human) 8778
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