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Invitrogen
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PA1-31010 detects SIRT4 from human samples. Expected to cross-react with mouse and rat samples due to sequence homology.
PA1-31010 has been successfully used in Western blot applications. PA1-31010 detects a band of ~40 kDa in human kidney and U937 lysates.
The PA1-31010 immunogen is: Synthetic peptide: SRCGELLPLIDPC.
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.
仅用于科研。不用于诊断过程。未经明确授权不得转售。