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Proteintech
SIX2 Polyclonal Antibody
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产品信息
11562-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human,
Mouse,
Pig,
Rat,
Reptile
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SIX2 Fusion Protein Ag2124 (1-291 aa encoded by BC024033)
偶联物
形式
Liquid
浓度
0.52 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
This antibody is a rabbit polyclonal antibody raised against full length SIX2 of human origin.
Immunogen sequence: MSMLPTFGF TQEQVACVCE VLQQGGNIER LGRFLWSLPA CEHLHKNESV LKAKAVVAFH RGNFRELYKI LESHQFSPHN HAKLQQLWLK AHYIEAEKLR GRPLGAVGKY RVRRKFPLPR SIWDGEETSY CFKEKSRSVL REWYAHNPYP SPREKRELTE ATGLTTTQVS NWFKNRRQRD RAAEAKEREN NENSNSNSHN PLNGSGKSVL GSSEDEKTPS GTPDHSSSSP ALLLSPPPPG LPSLHSLGHP PGPSAVPVPV PGGGGADPLQ HHHGLQDSIL NPMSANLVDL GS (1-291 aa encoded by BC024033)
靶标信息
This gene is a member of the vertebrate gene family which encode proteins homologous to the Drosophila 'sine oculis' homeobox protein. SIX2 is a transcription factor which, like other members of this gene family, may be involved in limb or eye development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Homeobox protein SIX2; Sine oculis homeobox homolog 2
基因别名: SIX2
UniProt ID: (Human) Q9NPC8
Entrez Gene ID: (Human) 10736
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription factor binding
protein complex binding
homeodomain transcription factor
kidney development
chondrocyte differentiation
mesenchymal to epithelial transition involved in metanephros morphogenesis
transcription from RNA polymerase II promoter
protein import into nucleus
mesodermal cell fate specification
cell proliferation
anatomical structure morphogenesis
anterior/posterior axis specification
cell migration
regulation of ossification
regulation of chondrocyte differentiation
middle ear morphogenesis
negative regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
embryonic digestive tract morphogenesis
embryonic cranial skeleton morphogenesis
nephron development
nephron morphogenesis
mesenchymal stem cell maintenance involved in nephron morphogenesis
mesenchymal cell differentiation involved in kidney development
regulation of branching involved in ureteric bud morphogenesis
mesenchymal stem cell proliferation
positive regulation of chondrocyte proliferation
