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Invitrogen
SLC16A13 Polyclonal Antibody
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产品信息
PA5-71529
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 398-426 amino acids from the C-terminal region of human SLC16A13
偶联物
形式
Liquid
浓度
0.5 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
靶标信息
Monocarboxylates, such as lactate and pyruvate, play an integral role in cellular metabolism. Lactic acid is produced in large quantities as a result of glycolysis, which provides the majority of ATP to cells under normal physiological conditions. However, accumulation of lactic acid leads to a decrease in intracellular pH and, thus, to a cessation of glycolysis. In order for glycolysis to continue at a high rate, lactic acid must be transported out of the cell. This transport process is carried out by a family of monocarboxylate transporters (MCTs), which function as proton symports and are stereoselective for L-lactate. MCT13 (Monocarboxylate transporter 13), also known as SLC16A13 (Solute carrier family 16 member 13), is a 426 amino acid multi-pass membrane protein that belongs to the MCT transport family. Functioning as a proton-linked monocarboxylate transporter, MCT13 catalyzes the rapid transports of molecules, such as lactate, across the plasma membrane.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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