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Invitrogen
SLC25A10 Polyclonal Antibody
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SLC25A10 Antibody (PA5150550) in IHC (P)
Immunohistochemistry analysis of SLC25A10 using paraffin-embedded human kidney (shows strong cytoplasmic granular positivity in cells in tubules and strong cytoplasmic membranous positivity in cells in glomeruli). Samples were incubated with SLC25A10 polyclonal antibody (Product # PA5150550).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5150550
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.05 mg/mL
规格
5 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Highest antigen sequence identity to the following orthologs: Mouse- 80%, Rat- 80%.
Sequence of this protein is as follows: SLTRFAIYET VRDRVAKGSQ GPLPFHEKVL LGSVSGLAGG FVGTPADLVN VRMQNDVKLP QGQRRNYAHA L
靶标信息
The mitochondrial dicarboxylate carrier protein (mDIC) belongs to superfamily of mitochondrial transporters. It has been demonstrated that the expression of mDIC leads to hyperpolarization of the mitochondria, as well as succinate uptake by the mitochondria. It is highly expressed in adipose tissue, where its expression is downregulated by insulin and upregulated by free fatty acids. mDIC is also thought to play a role in glyceroneogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: dicarboxylate ion carrier; solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter) member 10 isoform SLC25A10_1; solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter) member 10 isoform SLC25A10_2; solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter) member 10 isoform SLC25A10_3; solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10; unnamed protein product
基因别名: DIC; MTDPS19
UniProt ID: (Human) Q9UBX3
Entrez Gene ID: (Human) 1468
dicarboxylic acid transmembrane transporter activity
protein binding
sulfate transmembrane transporter activity
thiosulfate transmembrane transporter activity
oxaloacetate transmembrane transporter activity
malate transmembrane transporter activity
succinate transmembrane transporter activity
secondary active transmembrane transporter activity
gluconeogenesis
dicarboxylic acid transport
thiosulfate transport
oxaloacetate transport
sulfide oxidation
phosphate ion transmembrane transport
glyceraldehyde-3-phosphate biosynthetic process
transmembrane transport
succinate transmembrane transport
malate transmembrane transport
oxaloacetate(2-) transmembrane transport
sulfate transmembrane transport
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
