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Invitrogen
SLC25A14 Polyclonal Antibody
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SLC25A14 Antibody (PA5-89394) in WB
Western blot analysis of SLC25A14 in extracts of various cell lines. Samples were incubated with SLC25A14 Polyclonal antibody (Product # PA5-89394) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-89394
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 25-200 of human SLC25A14 (NP_0012691241)
偶联物
形式
Liquid
浓度
0.94 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: Mouse brain, Rat brain; Cellular Location: Mitochondrion inner membrane, Multi-pass membrane protein
Immunogen sequence: GHQKSTTVSH EMSGLNWKPF VYGGLASIVA EFGTFPVDLT KTRLQVQGQS IDARFKEIKY RGMFHALFRI CKEEGVLALY SGIAPALLRQ ASYGTIKIGI YQSLKRLFVE RLEDETLLIN MICGVVSGVI SSTIANPTDV LKIRMQAQGS LFQGSMIGSF IDIYQQEGTR GLWRGV
靶标信息
Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is widely expressed in many tissues with the greatest abundance in brain and testis. The gene product has an N-terminal hydrophobic domain that is not present in other UCPs. Two splice variants have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: BMCP-1; Brain mitochondrial carrier protein 1; Mitochondrial uncoupling protein 5; solute carrier family 25 (mitochondrial carrier, brain), member 14; Solute carrier family 25 member 14; UCP 5
基因别名: BMCP1; SLC25A14; UCP5; UCP5L; UCP5S; UNQ791/PRO1682
UniProt ID: (Human) O95258, (Mouse) Q9Z2B2
Entrez Gene ID: (Human) 9016, (Mouse) 20523, (Rat) 85263
