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Abnova
SLC25A36 Polyclonal Antibody, MaxPab™
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00055186-B02P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SLC25A36 (AAH14064, 1 a.a. approximately 311 a.a) full-length human protein.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5-1 mg/mL
规格
50 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MSQRDTLVHL FAGGCGGTVG AILTCPLEVV KTRLQSSSVT LYISEVQLNT MAGASVNRVV SPGPLHCLKV ILEKEGPRSL FRGLGPNLVG VAPSRAIYFA AYSNCKEKLN DVFDPDSTQV HMISAAMAGF TAITATNPIW LIKTRLQLDA RNRGERRMGA FECVRKVYQT DGLKGFYRGM SASYAGISET VIHFVIYESI KQKLLEYKTA STMENDEESV KEASDFVGMM LAAATSKTCA TTIAYPHEVV RTRLREEGTK YRSFFQTLSL LVQEEGYGSL YRGLTTHLVR QIPNTAIMMA TYELVVYLLN G
靶标信息
The SLC25A36 gene is part of the solute carrier family 25 (SLC25), which encodes mitochondrial transport proteins. SLC25A36 specifically functions as a transporter of pyrimidine nucleotides, including deoxynucleotide triphosphates, across the inner mitochondrial membrane. This transport is essential for maintaining mitochondrial DNA synthesis and repair, as well as for the proper functioning of mitochondrial ribonucleotide reductase. The SLC25A36 protein exhibits a characteristic transmembrane structure with six transmembrane helices and a central substrate-binding site. It operates via a mechanism involving substrate binding, conformational changes, and alternating access to the substrate-binding site from either side of the membrane. Dysregulation or mutations in SLC25A36 can lead to mitochondrial dysfunction and are associated with various metabolic disorders.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
