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Invitrogen
SLC4A4 (extracellular) Polyclonal Antibody
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SLC4A4 (extracellular) Antibody (PA5-77550) in ICC/IF
Immunocytochemistry analysis of SLC4A4 (extracellular) in rat PC12 pheochromocytoma cells. A) Samples were probed with SLC4A4 (extracellular) polyclonal antibody (Product # PA5-77550) using a dilution of 1:100, and incubated with goat-anti-rabbit-AlexaFluor-594. B) Live view image. C) Merged image of Panels A and B.
产品信息
PA5-77550
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide (C)KE(S)VKFGGKLVGNN, corresponding to amino acid residues 672-685 of rat NBCe1
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
产品详细信息
Product is shipped at room temperature as a lyophilized powder and should be stored at -20C upon receipt.
Reconstitute using 50 uL deionized water.
靶标信息
Slc4a4 encodes a sodium bicarbonate cotransporter (NBC) involved in the regulation of bicarbonate secretion and absorption and intracellular pH. Slc4a4 is an electrogenic sodium/bicarbonate cotransporter with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3. Moreover, Slc4a4 may regulate bicarbonate influx/efflux at the basolateral membrane of cells and regulate intracellular pH. Isoform 2: May have a higher activity than isoform 1. Mutations in the Slc4a4 gene are associated with proximal renal tubular acidosis. Multiple transcript variants encoding different isoforms have been found for the Slc4a4 gene. Diseases associated with SLC4A4 include Renal Tubular Acidosis, Proximal, With Ocular Abnormalities and Proximal Renal Tubular Acidosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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