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Proteintech
SLC4A8 Polyclonal Antibody
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产品信息
12531-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SLC4A8 Fusion Protein Ag3227 (1-352 aa encoded by BC025994)
偶联物
形式
Liquid
浓度
0.18 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MPAAGSNEP DGVLSYQRPD EEAVVDQGGT STILNIHYEK EELEGHRTLY VGVRMPLGRQ SHRHHRTHGQ KHRRRGRGKG ASQGEEGLEA LAHDTPSQRV QFILGTEEDE EHVPHELFTE LDEICMKEGE DAEWKETARW LKFEEDVEDG GERWSKPYVA TLSLHSLFEL RSCLINGTVL LDMHANSIEE ISDLILDQQE LSSDLNDSMR VKVREALLKK HHHQNEKKRN NLIPIVRSFA EVGKKQSDPH LMDKHGQTVS PQSVPTTNLE VKNGVNCEHS PVDLSKVDLH FMKKIPTGAE ASNVLVGEVD ILDRPIVAFV RLSPAVLLSG LTEVPIPTRF LFILLGPVGK GQQ (1-352 aa encoded by BC025994)
靶标信息
Mediates electroneutral sodium- and carbonate-dependent choride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Electroneutral Na(+)-driven Cl-HCO3 exchanger; Electroneutral Na+-driven Cl-HCO3 exchanger; Electroneutral sodium bicarbonate exchanger 1; k-NBC3; Na-driven Cl-HCO3 exchanger NDCBE1-A; Na-driven Cl-HCO3 exchanger NDCBE1-B; Na-driven Cl-HCO3 exchanger NDCBE1-C; slc4a8; slc4a8 {ECO:0000312|RGD:735164}; sodium bicarbonate cotransporter isoform 3 kNBC-3; solute carrier family 4 (anion exchanger), member 8; Solute carrier family 4 member 8; solute carrier family 4, sodium bicarbonate cotransporter, member 8
基因别名: AW493845; C230026C11; KIAA0739; kNBC-3; NBC; NBC3; NDCBE; NDCBE1; SLC4A8
UniProt ID: (Human) Q2Y0W8, (Mouse) Q8JZR6, (Rat) Q6RVG2
Entrez Gene ID: (Human) 9498, (Mouse) 59033, (Rat) 315311
