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Invitrogen
SLC6A12 Polyclonal Antibody
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SLC6A12 Antibody (PA5-104148) in ICC/IF
Immunocytochemistry analysis of SLC6A12 in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with SLC6A12 polyclonal antibody (Product # PA5-104148) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-104148
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human SLC6A12(Accession P48065), corresponding to amino acid residues T557-A607.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total SLC6A12.
靶标信息
Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Betaine/GABA transporter 1; betaine/GABA transporter-1; BGT-1; GABA transporter 1; gamma-aminobutyric acid (GABA-A) transporter 2; gamma-aminobutyric acid transporter; GAT-2; Na(+)/Cl(-) betaine/GABA transporter; Sodium- and chloride-dependent betaine transporter; sodium- and chloride-dependent GABA transporter 2; solute carrier family 6 (neurotransmitter transporter), member 12; solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12; Solute carrier family 6 member 12; unnamed protein product; vesicular GABA transporter
基因别名: BGT-1; BGT1; Gabt2; Gat1; GAT2; RNU28927; SLC6A12; VGAT
UniProt ID: (Rat) P48056
Entrez Gene ID: (Human) 6539, (Mouse) 14411, (Rat) 50676
gamma-aminobutyric acid:sodium symporter activity
protein binding
monocarboxylic acid transmembrane transporter activity
amino acid transmembrane transporter activity
transmembrane transporter activity
glycine betaine:sodium:chloride symporter activity
neurotransmitter:sodium symporter activity
symporter activity
primary active transporter
amino acid transmembrane transport
neurotransmitter transport
amino acid transport
monocarboxylic acid transport
gamma-aminobutyric acid transport
glycine betaine transport
sodium ion transmembrane transport
gamma-aminobutyric acid reuptake
transport
cellular water homeostasis
response to organic substance
transmembrane transport
cellular hyperosmotic response
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