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Invitrogen
SLC7A5 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-34215
产品规格
种属反应
Dog,
Human,
Non-human primate
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 15 amino acid peptide from internal region of human SLC7A5.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.6 mg/mL
规格
50 µg
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Percent identity with other species by BLAST analysis: Monkey, Marmoset, Dog (100%) Human, Panda, Bat, Rabbit (93%) Elephant, Bovine, Horse (87%).
靶标信息
Solute carrier family 7 member 5 also known as large neutral amino acids transporter small subunit 1 is a protein that in humans is encoded by the SLC7A5 gene.It is sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc.It involved in cellular amino acid uptake and the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta.Acts as an amino acid exchanger and plays a role in neuronal cell proliferation (neurogenesis) in brain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 4F2; 4F2 light chain; 4F2HC; 4T2HC; CD98 light chain; CD98HC; E16; integral membrane protein E16; L-type amino acid transporter 1; LAT1; MDU1; MP hLAT1; NACAE; sodium-independent neutral amino acid transporter LAT1; solute carrier family 7 (amino acid transporter light chain, L system), member 5; solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
基因别名: 4F2LC; CD98; D16S469E; E16; LAT1; MPE16
UniProt ID: (Human) Q01650
Entrez Gene ID: (Human) 8140, (Dog) 489667
protein binding
amino acid transmembrane transporter activity
aromatic amino acid transmembrane transporter activity
neutral amino acid transmembrane transporter activity
L-amino acid transmembrane transporter activity
L-leucine transmembrane transporter activity
L-tryptophan transmembrane transporter activity
antiporter activity
thyroid hormone transmembrane transporter activity
transmembrane transporter activity
peptide antigen binding
transporter
positive regulation of cytokine production involved in immune response
amino acid transmembrane transport
amino acid transport
negative regulation of autophagy
negative regulation of gene expression
response to muscle activity
neutral amino acid transport
L-amino acid transport
isoleucine transport
leucine transport
methionine transport
phenylalanine transport
proline transport
tryptophan transport
tyrosine transport
valine transport
alanine transport
positive regulation of interferon-gamma production
positive regulation of interleukin-17 production
positive regulation of interleukin-4 production
cellular response to glucose starvation
xenobiotic transport
transmembrane transport
response to hyperoxia
positive regulation of glial cell proliferation
thyroid hormone transport
cellular response to lipopolysaccharide
cellular response to amino acid stimulus
amino acid import across plasma membrane
liver regeneration
transport across blood-brain barrier
L-histidine transport
L-alpha-amino acid transmembrane transport
cellular response to L-arginine
L-leucine import across plasma membrane
L-tryptophan transmembrane transport
negative regulation of vascular associated smooth muscle cell apoptotic process
positive regulation of leucine import across plasma membrane
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