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Invitrogen
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Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 µL of deionized water.
Na+/H+ exchangers-1-6 (Na+/H+ antiporters, NHE-1-6) are integral membrane proteins that are expressed in most mammalian tissues, where they regulate intracellular pH and cell volume. NHEs mediate the secondary active extrusion of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+). Excluding NHE-1, which is ubiquitously expressed, NHE isoforms 2-6 have distinct tissue- and cell type-dependent expression and inhibitiory characteristics by amiloride analogs. Human NHE-5 transcript (solute carrier family 9, isoform-5, SLC9A5) is an 896 amino acid protein that is expressed in brain, testis, spleen and skeletal muscle.
仅用于科研。不用于诊断过程。未经明确授权不得转售。