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Alomone Labs, LTD
SLIT1 Polyclonal Antibody
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SLIT1 Antibody (ANR-221-200UL) in IHC (F)
Expression of SLIT1 in mouse cerebellum. Immunohistochemical staining of perfusion-fixed frozen mouse brain sections using Anti-SLIT1 Antibody (#ANR-221) (1:300), followed by goat anti-rabbit-AlexaFluor-488. A. SLIT1 immunoreactivity (green), appears in Purkinje cells (vertical arrows) and their dendritic tree (horizontal arrows). B. Pre-incubation of the antibody with SLIT1 Blocking Peptide (#BLP-NR221), s... View More
产品信息
ANR-221-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide RSYSTTYEERNITGTR, corresponding to amino acid residues 202-217 of human ASCT2. Extracellular, 2nd loop.
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Immunogen sequence: RSYSTTYEERNITGTR
Reconstitution: 50 uL double distilled water (DDW). The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
SLIT1 is thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Multiple EGF-like domains protein 4; multiple epidermal growth factor-like domains 4; Multiple epidermal growth factor-like domains protein 4; slit homolog 1; Slit homolog 1 protein; Slit-1
基因别名: KIAA0813; MEGF4; mKIAA0813; SLIL1; SLIT-1; SLIT1; SLIT3
UniProt ID: (Human) O75093, (Rat) O88279, (Mouse) Q80TR4
Entrez Gene ID: (Human) 6585, (Rat) 65047, (Mouse) 20562
axon guidance
motor neuron axon guidance
chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration
retinal ganglion cell axon guidance
dorsal/ventral axon guidance
Roundabout signaling pathway
establishment of nucleus localization
axon extension involved in axon guidance
forebrain morphogenesis
regulation of axonogenesis
negative chemotaxis
negative regulation of synapse assembly
axonogenesis
brain development
spinal cord development
olfactory bulb development
tangential migration from the subventricular zone to the olfactory bulb
telencephalon cell migration
neuron projection morphogenesis
negative regulation of axon extension involved in axon guidance
multicellular organism development
nervous system development
cell differentiation
