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Invitrogen
SMU1 Polyclonal Antibody
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SMU1 Antibody (PA5-121223) in WB
Western blot analysis of SMU1 in extracts of various cell lines. Samples were incubated with SMU1 Polyclonal antibody (Product # PA5-121223) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
产品信息
PA5-121223
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human SMU1 (NP_060695.2).
偶联物
形式
Liquid
浓度
4.62 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive test controls include: HeLa, A-431, HT-29, Mouse liver, Mouse intestine. The target is usually found in the following locations: Cytoplasm, Nucleus.
Immunogen sequence: MSIEIESSDV IRLIMQYLKE NSLHRALATL QEETTVSLNT VDSIESFVAD INSGHWDTVL QAIQSLKLPD KTLIDLYEQV VLELIELREL GAARSLLRQT DPMIMLKQTQ PERYIHLENL LARSYFDPRE AYPDGSSKEK RRAAIAQALA GEVSVVPPSR LMALLGQALK WQQHQGLLPP GMTIDLFRGK AAVKDVEEEK FPTQLSRHIK FGQKSHVECA
靶标信息
SMU1 (suppressor of Mec8 and Unc-52 homolog), also known as BWD (brain-enriched WD), is a member of the WD-repeat SMU1 family and contains one CTLH domain, one LisH domain and six WD-repeats. SMU1 is a homolog of the C. elegans protein Smu1, a ubiquitously expressed nuclear protein that is believed to play a role in alternative splicing events of Unc-52. In mammals, SMU1 is a component of the spliceosome and appears to exhibit a conserved function, affecting the splicing of the mammalian Unc-52 homolog, namely Perlecan. Mutations in the gene encoding SMU1 may affect the function of the spliceosome.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Brain-enriched WD repeat-containing protein; brain-enriched WD-repeat protein; functional spliceosome-associated protein 57; homolog of C. elegans smu-1; smu-1 suppressor of mec-8 and unc-52 homolog; Smu-1 suppressor of mec-8 and unc-52 protein homolog; suppressor of Mec and Unc defects 1 homolog; WD40 repeat-containing protein SMU1
基因别名: 2600001O03Rik; 2610203K23Rik; AB044414; AI845086; AW556129; BWD; fSAP57; SMU-1; SMU1
UniProt ID: (Human) Q2TAY7, (Mouse) Q3UKJ7, (Rat) Q99M63
Entrez Gene ID: (Human) 55234, (Mouse) 74255, (Rat) 117541
