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Proteintech
SND1 Monoclonal Antibody (1A6A4)
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产品信息
60265-1-IG
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
1A6A4
抗原
SND1 Fusion Protein Ag1200 (548-911 aa encoded by BC017180)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: TCLITFLLA GIECPRGARN LPGLVQEGEP FSEEATLFTK ELVLQREVEV EVESMDKAGN FIGWLHIDGA NLSVLLVEHA LSKVHFTAER SSYYKSLLSA EEAAKQKKEK VWAHYEEQPV EEVMPVLEEK ERSASYKPVF VTEITDDLHF YVQDVETGTQ LEKLMENMRN DIASHPPVEG SYAPRRGEFC IAKFVDGEWY RARVEKVESP AKIHVFYIDY GNREVLPSTR LGTLSPAFST RVLPAQATEY AFAFIQVPQD DDARTDAVDS VVRDIQNTQC LLNVEHLSAG CPHVTLQFAD SKGDVGLGLV KEGLVMVEVR KEKQFQKVIT EYLNAQESAK SARLNLWRYG DFRADDADEF GYSR (548-911 aa encoded by B C017180)
靶标信息
SND1/P100 (staphylococcal nuclease and tudor domain containing 1), also known as TudorSN, functions in the Pim-1 regulation of Myb activity and acts as a transcriptional activator of EBNA-2. It also interacts with EAV, NSP1, GTF2E1 and GTF2E2, and forms a ternary complex with Stat6 and POLR2A. The staphylococcal nuclease-like (SN)-domains directly interact with amino acids 1099-1758 of CBP. SND1/P100 plays an important role in the assembly of Stat6 transcriptome and stimulates IL-4-dependent transcription by mediating interaction between Stat6 and CBP.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 100 kDa coactivator; EBNA-2 co-activator (100kD); EBNA2 coactivator p100; p100 co-activator; p100 EBNA2 co-activator; p105 coactivator; SND p102; SND1-BRAF fusion; staphylococcal nuclease domain containing 1; Staphylococcal nuclease domain-containing protein 1; testis tissue sperm-binding protein Li 82P; Tudor domain-containing protein 11; Tudor-SN; TudorSN
基因别名: AL033314; p100; SND p102; SND1; TDRD11; Tudor-SN
UniProt ID: (Human) Q7KZF4, (Rat) Q66X93, (Mouse) Q78PY7
Entrez Gene ID: (Human) 27044, (Rat) 64635, (Mouse) 56463
