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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: TCLITFLLA GIECPRGARN LPGLVQEGEP FSEEATLFTK ELVLQREVEV EVESMDKAGN FIGWLHIDGA NLSVLLVEHA LSKVHFTAER SSYYKSLLSA EEAAKQKKEK VWAHYEEQPV EEVMPVLEEK ERSASYKPVF VTEITDDLHF YVQDVETGTQ LEKLMENMRN DIASHPPVEG SYAPRRGEFC IAKFVDGEWY RARVEKVESP AKIHVFYIDY GNREVLPSTR LGTLSPAFST RVLPAQATEY AFAFIQVPQD DDARTDAVDS VVRDIQNTQC LLNVEHLSAG CPHVTLQFAD SKGDVGLGLV KEGLVMVEVR KEKQFQKVIT EYLNAQESAK SARLNLWRYG DFRADDADEF GYSR (548-911 aa encoded by B C017180)
SND1/P100 (staphylococcal nuclease and tudor domain containing 1), also known as TudorSN, functions in the Pim-1 regulation of Myb activity and acts as a transcriptional activator of EBNA-2. It also interacts with EAV, NSP1, GTF2E1 and GTF2E2, and forms a ternary complex with Stat6 and POLR2A. The staphylococcal nuclease-like (SN)-domains directly interact with amino acids 1099-1758 of CBP. SND1/P100 plays an important role in the assembly of Stat6 transcriptome and stimulates IL-4-dependent transcription by mediating interaction between Stat6 and CBP.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 100 kDa coactivator; EBNA2 coactivator p100; p100 co-activator; p105 coactivator; staphylococcal nuclease domain containing 1; testis tissue sperm-binding protein Li 82P; tudor domain-containing protein 11; TudorSN; unnamed protein product
基因别名: p100; SND p102; TDRD11; TSN; Tudor-SN
UniProt ID: (Human) Q7KZF4, (Rat) Q66X93, (Mouse) Q78PY7
Entrez Gene ID: (Human) 27044, (Rat) 64635, (Mouse) 56463