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Invitrogen
SNRPA1 Polyclonal Antibody
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SNRPA1 Antibody (PA5-88387) in IHC (P)
Immunohistochemistry analysis of SNRPA1 in paraffin-embedded human esophageal cancer. Samples were incubated with SNRPA1 Polyclonal antibody (Product # PA5-88387) using a dilution of 1:200 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
产品信息
PA5-88387
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human SNRPA1 (NP_0030812)
偶联物
形式
Liquid
浓度
0.69 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MVKLTAELIE QAAQYTNAVR DRELDLRGYK IPVIENLGAT LDQFDAIDFS DNEIRKLDGF PLLRRLKTLL VNNNRICRIG EGLDQALPCL TELILTNNSL VELGDLDPLA SLKSLTYLSI LRNPVTNKKH YRLYVIYKVP QVRVLDFQKV KLKERQEAEK MFKGKRGAQL AKDIARRSKT FNPGAGLPTD KKKGGPSPGD VEAIKNAIAN ASTLAEVERL; Positive Samples: HT-29, Jurkat, Raji, HeLa, NIH/3T3, Mouse kidney, Mouse liver, Mouse lung; Cellular Location: Nucleus
靶标信息
SNRPA1 (U2 snRNP-A) is located in gene map locus 15q26. 3 and is a 28 kDa protein, isa specific component of U2 snRNP particle and consists of a unique N-terminal leucine-rich region and an extremely hydrophobic RNA-binding C-terminal region. It lacks segments homologous to RNP1 and RNP2, commonA. A motifs found in several RNA-binding proteins. It associates with U2 snRNP and participates in transcription and pre-mRNA splicing. It might play an important role in cell division and proliferation. Patients with connective tissue disorders often produce autoantibodies against snRNP particles.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: U2 small nuclear ribonucleoprotein A'; U2 small nuclear ribonucleoprotein polypeptide A'; U2 snRNP A'; U2 snRNP-A'
基因别名: 1500015N06Rik; Lea1; SNRPA1
UniProt ID: (Human) P09661, (Mouse) P57784
Entrez Gene ID: (Human) 6627, (Mouse) 68981, (Rat) 100361269
