Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
SNRPN Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
图: 1 / 12
SNRPN Antibody (PA5-80047) in ICC/IF
Immunocytochemistry analysis of SNRPN using anti-SNRPN antibody (Product # PA5-80047) . SNRPN was detected in an immunocytochemical section of CACO-2 cells. Enzyme antigen retrieval was performed using IHC enzyme antigen retrieval reagent for 15 mins. The cells were blocked with 10% goat serum and then incubated with 5 μg/mL rabbit anti-SNRPN antibody (Product # PA5-80047) overnight at 4°C. DyLight®488 Conjugated Goat Anti-Rabbit IgG was used as secondary antibody at 1:100 dilution and incubated for 30 minutes at 37°C. The section was coun... View More
产品信息
PA5-80047
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence at the N-terminus of human SNRPN (11-39aa QHIDYRMRCILQDGRIFIGTFKAFDKHMN).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human U87 whole cell, human Hela whole cell, human THP-1 whole cell, human RT4 whole cell, rat brain tissue, mouse brain tissue. IHC: human cervical cancer tissue, human breast cancer tissue, human colorectal adenocarcinoma tissue, human lymphoma tissue, human ovarian serous adenocarcinoma tissue, mouse brain tissue, rat brain tissue. ICC/IF: CACO-2 cell.
靶标信息
The protein encoded by this gene is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. The protein plays a role in pre-mRNA processing, possibly tissue-specific alternative splicing events. Although individual snRNPs are believed to recognize specific nucleic acid sequences through RNA-RNA base pairing, the specific role of this family member is unknown. The protein arises from a bicistronic transcript that also encodes a protein identified as the SNRPN upstream reading frame (SNURF). Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region. Additional splice variants have been described but sequences for the complete transcripts have not been determined. The 5' UTR of this gene has been identified as an imprinting center. Alternative splicing or deletion caused by a translocation event in this paternally-expressed region is responsible for Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: DKFZp686C0927; DKFZp686M12165; DKFZp761I1912; DKFZp762N022; FE294 gene for snRNP-associated polypeptide N; FE294 psi pseudogene; FLJ33569; FLJ36996; FLJ39265; MGC29886; Sm protein D; SM protein N; Sm-D; Sm-N; small nuclear ribonucleoparticle-associated protein (snRNP) mRNA clone Sm51; small nuclear ribonucleoparticle-associated protein (snRNP) mRNA, clone Sm51; small nuclear ribonucleoprotein N; Small nuclear ribonucleoprotein-associated protein N; smN; snRNP-N; tissue-specific splicing protein; Tissue-specific-splicing protein
基因别名: 2410045I01Rik; FE 294; FE 294 psi; FE294; FE294 psi; HCERN3; Peg4; PWCR; Pwcr1; RT-LI; SM-D; sm-N; SMN; SNRNP-N; SNRPN; SNURF-SNRPN
UniProt ID: (Human) P63162, (Rat) P63164, (Mouse) P63163
Entrez Gene ID: (Human) 6638, (Rat) 81781, (Mouse) 20646
