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Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Raji.
Predicted reactivity: Mouse (96%), Rat (96%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Syntrophins are structurally related proteins located at the neuromuscular synapse and play an important role in dystrophin associated protein (DAP) complex formation. To date there have been three distinct syntrophin isoforms discovered: alpha 1, beta 1, and beta 2. These proteins each contain a PDZ domain, a syntrophin-unique domain (SU), and three pleckstrin homology domains (PH1a,1b and 2). The PDZ domain has been shown to be responsible for binding syntrophin to nNOS and the DAP complex. This association results in localization of the nicotinic acetylcholine receptor to the cytoskeleton via the (S/T)XV C terminus.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 59 kDa dystrophin-associated protein A1 basic component 2; Beta-2-syntrophin; dystrophin-associated protein A1, 59kD, basic component 2; SNT3; SNTL; SYN; syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2); Syntrophin-3; Syntrophin-like
基因别名: D16S2531E; EST25263; SNT2B2; SNT3; SNTB2; SNTL
UniProt ID: (Human) Q13425
Entrez Gene ID: (Human) 6645