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Proteintech
SOX12 Polyclonal Antibody
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产品信息
23939-1-AP
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SOX12 Fusion Protein Ag21043 (1-315 aa encoded by BC067361)
偶联物
形式
Liquid
浓度
0.33 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MVQQRGARA KRDGGPPPPG PGPAEEGARE PGWCKTPSGH IKRPMNAFMV WSQHERRKIM DQWPDMHNAE ISKRLGRRWQ LLQDSEKIPF VREAERLRLK HMADYPDYKY RPRKKSKGAP AKARPRPPGG SGGGSRLKPG PQLPGRGGRR AAGGPLGGGA AAPEDDDEDD DEELLEVRLV ETPGRELWRM VPAGRAARGQ AERAQGPSGE GAAAAAAASP TPSEDEEPEE EEEEAAAAEE GEEETVASGE ESLGFLSRLP PGPAGLDCSA LDRDPDLQPP SGTSHFEFPD YCTPEVTEMI AGDWRPSSIA DLVFTY (1-315 aa encoded by B C067361)
靶标信息
Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain, homologous to the HMG box of sex-determining region Y (SRY). Forming a subgroup of the HMG domain superfamily, SOX proteins have been implicated in cell fate decisions in a diverse range of developmental processes. SOX transcription factors have diverse tissue-specific expression patterns during early development and have been proposed to act as target-specific transcription factors and/or as chromatin structure regulatory elements. The protein encoded by this gene was identified as a SOX family member based on conserved domains, and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Protein SOX-22; SOX-22 protein; SRY (sex determining region Y)-box 12; SRY box 12; SRY-box containing gene 12; SRY-related HMG-box gene 22; Transcription factor SOX-12
基因别名: 2010205A02Rik; Sox-12; SOX12; SOX22
UniProt ID: (Human) O15370, (Mouse) Q04890
Entrez Gene ID: (Human) 6666, (Mouse) 20667
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
spinal cord development
cell fate commitment
positive regulation of transcription from RNA polymerase II promoter
protein-DNA complex assembly
transcription, DNA-templated
regulation of transcription, DNA-templated
