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Abnova
SOX13 Monoclonal Antibody (3E8)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00009580-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
3E8
抗原
SOX13 (NP_005677, 25 a.a. approximately 138 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: KSEEKKEPCH EAPQGSATAA EPQPGDPARA SQDSADPQAP AQGNFRGSWD CSSPEGNGSP EPKRPGVSEA ASGSQEKLDF NRNLKEVVPA IEKLLSSDWK ERFLGRNSME AKDV
靶标信息
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. It has also been determined to be a type-1 diabetes autoantigen, also known as islet cell antibody 12.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: islet cell antibody 12; islet cell antigen 12; MGC117216; RP11-74C13.1; SRY (sex determining region Y)-box 13; SRY-box 13; SRY-related HMG-box gene 13; type 1 diabetes autoantigen ICA12; unnamed protein product
基因别名: ICA12; Sox-13
UniProt ID: (Human) Q9UN79
Entrez Gene ID: (Human) 9580
transcription regulatory region sequence-specific DNA binding
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
identical protein binding
sequence-specific DNA binding
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
anatomical structure morphogenesis
spinal cord oligodendrocyte cell differentiation
gamma-delta T cell differentiation
cell fate commitment
positive regulation of gamma-delta T cell differentiation
negative regulation of transcription, DNA-templated
negative regulation of canonical Wnt signaling pathway
positive regulation of brown fat cell differentiation
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
