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Abnova
SOX5 Monoclonal Antibody (4H8)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00006660-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
4H8
抗原
SOX5 (NP_008871.3, 181 a.a. approximately 230 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.24 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: GSGNFGEIKG TPESLAEKER QLMGMINQLT SLREQLLAAH DEQKKLAASQ
靶标信息
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The encoded protein may play a role in chondrogenesis. A pseudogene of this gene is located on chromosome 8. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MGC35153; SOX5; SRY (sex determining region Y)-box 5; SRY-box 5; Sry-related HMG box gene; unnamed protein product
基因别名: L-SOX5; L-SOX5B; L-SOX5F; LAMSHF
UniProt ID: (Human) P35711
Entrez Gene ID: (Human) 6660
transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter proximal region sequence-specific DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
cartilage condensation
chondrocyte differentiation
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
positive regulation of chondrocyte differentiation
cell fate commitment
cartilage development
asymmetric neuroblast division
positive regulation of cartilage development
cellular response to transforming growth factor beta stimulus
positive regulation of mesenchymal stem cell differentiation
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