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Invitrogen
SPANXB1 Polyclonal Antibody
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产品信息
PA5-45150
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the middle region of human SPANXB1
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Peptide sequence: MPETPTGDSD PQPAPKKMKT SESSTILVVR YRRNVKRTSP EELVNDHARE
Sequence homology: Human: 100%
靶标信息
Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene maps to chromosome X in a head-to-tail orientation with SPANX family member B2, which appears to be a duplication of the B1 locus. The SPANXB genes are unique members of this gene family, since they contain an additional 18 nt in their coding region compared to the majority of family members. Although the protein encoded by this gene contains consensus nuclear localization signals, the major site for subcellular localization of expressed protein is in the cytoplasmic droplets of ejaculated spermatozoa. This protein provides a biochemical marker for studying the unique structures in spermatazoa, while attempting to further define its role in spermatogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cancer/testis antigen 11.2; cancer/testis antigen family 11, member 2; CT11.2; Nuclear-associated protein SPAN-Xb; nuclear-associated protein SPAN-Xf; SPANX family member B/F; SPANX family member B1; SPANX family member F1; SPANX family, member B1; SPANX family, member B2; SPANX family, member F1; SPANX family, member F2; SPANX-B; sperm protein associated with the nucleus on the X chromosome B/F; Sperm protein associated with the nucleus on the X chromosome B1; sperm protein associated with the nucleus, X chromosome, family member B1
基因别名: B1; CT11.2; SPANX-B; SPANXB; SPANXB1; SPANXB2; SPANXF1; SPANXF2
UniProt ID: (Human) Q9NS25
Entrez Gene ID: (Human) 728695
