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Invitrogen
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Immunogen sequence: WNSNQATDIM ETSGWKSMIQ SHPHLVAEAF RALASAQCPQ FGIPRKRLKQ
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins, but with relatively low efficiency. Cullin-RING-based BCR (BTB-CUL3- RBX1) E3 ubiquitin-protein ligase complexes containing homodimeric SPOPL or the heterodimer formed by SPOP and SPOPL are less efficient than ubiquitin ligase complexes containing only SPOP. May function to down-regulate the activity of cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes that contain SPOP.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: HIB homolog 2; Roadkill homolog 2; speckle type POZ protein like; Speckle-type POZ protein-like
基因别名: BTBD33; SPOPL
UniProt ID: (Human) Q6IQ16
Entrez Gene ID: (Human) 339745