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Proteintech
SPPL2A Polyclonal Antibody
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产品信息
13255-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SPPL2A Fusion Protein Ag3935 (361-520 aa encoded by BC025740)
偶联物
形式
Liquid
浓度
0.23 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: ITKNGESIM VELAAGPFGN NEKLPVVIRV PKLIYFSVMS VCLMPVSILG FGDIIVPGLL IAYCRRFDVQ TGSSYIYYVS STVAYAIGMI LTFVVLVLMK KGQPALLYLV PCTLITASVV AWRRKEMKKF WKGNSYQMMD HLDCATNEEN PVISGEQIVQ Q (361-520 aa encoded by BC025740)
靶标信息
By searching sequence databases for homologs of Dictyostelium discoideum Impas, which shares homology with presenilin, followed by PCR of lymphocyte and hippocampus cDNA libraries, Grigorenko et al. (2002) cloned SPPL2a. This protein, which may act as an intramembrane protease, contains an N-terminal protease-associated (PA) domain, several transmembrane regions, a hydrophilic loop, conservative sequences around the first and second aspartate residues, and an invariant PAL motif near the C terminus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: IMP-3; intramembrane cleaving protease; Intramembrane protease 3; Presenilin-like protein 2; protein SPPL2a; Signal peptide peptidase-like 2A; SPP-like 2A; SPP-like 2A protein; SPPL2a protein
基因别名: 2010106G01Rik; C130089K23Rik; IMP3; MNCb-3763; PSEC0147; PSL2; RGD1563001; SPPL2A
UniProt ID: (Human) Q8TCT8, (Mouse) Q9JJF9
Entrez Gene ID: (Human) 84888, (Rat) 311401, (Mouse) 66552
