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Proteintech
SPRED2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
24091-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SPRED2 Fusion Protein Ag21359 (122-214 aa encoded by BC136334)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.13 mg/mL
规格
19.5 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: LIEGSTTSS STIHNEAELG DDDVFTTATD SSSNSSQKRE QPTRTISSPT SCEHRRIYTL GHLHDSYPTD HYHLDQPMPR PYRQVSFPDD DEEI (122-214 aa encoded by B C136334)
靶标信息
SPRED2 is a member of the Sprouty /SPRED family of proteins that regulate growth factor-induced activation of the MAP kinase cascade (Nonami et al., 2004 ).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: EVH1/Sprouty domain containing protein; spred-2; sprouty protein with EVH-1 domain 2, related sequence; unnamed protein product
基因别名: NS14; Spred-2
UniProt ID: (Human) Q7Z698, (Mouse) Q924S7, (Rat) Q3C2P8
Entrez Gene ID: (Human) 200734, (Mouse) 114716, (Rat) 305539
regulation of signal transduction
negative regulation of epithelial to mesenchymal transition
negative regulation of transforming growth factor beta receptor signaling pathway
negative regulation of MAPK cascade
positive regulation of DNA damage response, signal transduction by p53 class mediator
negative regulation of ERK1 and ERK2 cascade
negative regulation of intracellular signal transduction
negative regulation of lens fiber cell differentiation
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