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Bethyl Laboratories
SRC1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
A300-343A
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residues 600 and 650 of Human Nuclear Receptor Coactivator 1.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
phosphate/tris citrate, pH 7-8
内含物
0.09% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
靶标信息
Clone 1135 recognizes SRC-1, steroid-receptor coactivator-1. SRC-1 is a member of a gene family that functions in the full transcriptional activation of the steroid hormone receptor superfamily and contains intrinsic histone acetyltransferase activity. SRC-1 has a molecular weight of 160 kDa and has a basic helix-loop-helix (bHLH)-PAS domain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ASV; c-SRC; class E basic helix-loop-helix protein 74; Hin-2; Hin-2 protein; nuclear receptor coactivator protein 1; p60-Src; renal carcinoma antigen NY-REN-52; SRC-1; SRC-1 (-Q); steroid receptor coactivator 1; steroid receptor coactivator-1; unnamed protein product
基因别名: bHLHe42; bHLHe74; F-SRC-1; KAT13A; mNRC-1; NCoA-1; NRC-1; RIP160; SRC-1; SRC-a; SRC1
UniProt ID: (Human) Q15788, (Mouse) P70365
Entrez Gene ID: (Human) 8648, (Mouse) 17977
RNA polymerase II regulatory region sequence-specific DNA binding
DNA binding
chromatin binding
transcription cofactor activity
transcription coactivator activity
protein binding
ligand-dependent nuclear receptor binding
estrogen receptor binding
retinoic acid receptor binding
macromolecular complex binding
retinoid X receptor binding
protein dimerization activity
peptide-lysine-N-acetyltransferase activity
positive regulation of transcription from RNA polymerase II promoter by galactose
regulation of transcription, DNA-templated
lactation
male gonad development
response to hormone
bile acid and bile salt transport
cerebellum development
hippocampus development
hypothalamus development
cerebral cortex development
intracellular estrogen receptor signaling pathway
response to estradiol
response to retinoic acid
response to progesterone
cellular response to hormone stimulus
peroxisome proliferator activated receptor signaling pathway
mRNA transcription from RNA polymerase II promoter
positive regulation of apoptotic process
estrous cycle
positive regulation of neuron differentiation
positive regulation of transcription, DNA-templated
positive regulation of female receptivity
positive regulation of transcription from RNA polymerase II promoter
progesterone receptor signaling pathway
male mating behavior
regulation of cellular response to insulin stimulus
positive regulation of adipose tissue development
regulation of thyroid hormone mediated signaling pathway
labyrinthine layer morphogenesis
cellular response to Thyroglobulin triiodothyronine
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