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Proteintech
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Immunogen sequence: YVHKPPVHI RFDEISFVNF ARGTTTTRSF DFEIETKQGT QYTFSSIERE EYGKLFDFVN AKKLNIKNRG LKEGMNPSYD EYADSDEDQH DAYLERMKEE GKIREENAND SSDDSGEETD ESFNPGEEEE DVAEEFDSNA SASSSSNEGD SDRDEKKRKQ LKKAKMAKDR KSRKKPVEVK KGKDPNAPKR PMSAYMLWLN ASREKIKSDH PGISITDLSK KAGEIWKGMS KEKKEEWDRK AEDARRDYEK AMKEYEGGRG ESSKRDKSKK KKKVKVKMEK KSTPSRGSSS KSSSRQLSES FKSKEFVSSD ESSSGENKSK KKRRRSEDSE EEELASTPPS SEDSASGSDE (361-709 aa encoded by BC005116)
SPT16 and SSRP1 are found in all eurkaryotic cells and exists as part of an essential heterodimer complex. Together, SPT 16 and SSRP1 are a highly abundant nuclear complex that in mammals has been called FACT, or Facilitates Chromatin Transcription. FACT enhances the processivity of RNA polymerase II through nucleosomes. Evidence also points to a role for FACT in replication, possibly by enhancing DNA polymerase through nucleosomes as well.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Chromatin-specific transcription elongation factor 80 kDa subunit; cisplatin-DNA SSRP; facilitates chromatin remodeling 80 kDa subunit; Facilitates chromatin transcription complex 80 kDa subunit; Facilitates chromatin transcription complex subunit SSRP1; FACT 80 kDa subunit; FACT complex subunit SSRP1; FACTp80; high mobility group box; hSSRP1; Recombination signal sequence recognition protein 1; Structure-specific recognition protein 1; T160
基因别名: C81323; Ciidbp; FACT; FACT80; Hmg1-rs1; Hmgi-rs3; Hmgox; SSRP1; T160
UniProt ID: (Human) Q08945, (Rat) Q04931, (Mouse) Q08943
Entrez Gene ID: (Human) 6749, (Rat) 81785, (Mouse) 20833