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Invitrogen
ST5 Polyclonal Antibody
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ST5 Antibody (PA5-101138) in IHC (P)
Immunohistochemistry analysis of ST5 in rat testis tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with ST5 polyclonal antibody (Product # PA5-101138) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-101138
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human ST5(Accession P78524), corresponding to amino acid residues A417-T467.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total ST5.
靶标信息
This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DENN domain-containing protein 2B; DENN/MADD domain containing 2B; HeLa tumor suppression 1; p70; Suppression of tumorigenicity 5 protein
基因别名: 2010004M01Rik; 2610305K15Rik; Denn2b; DENND2B; HTS1; p126; ST5
UniProt ID: (Human) P78524, (Mouse) Q924W7
Entrez Gene ID: (Human) 6764, (Mouse) 76954
