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Invitrogen
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Immunogen sequence: NLWDCAGTQL KDWEGLTSLL LEKDQ
Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 80%.
STAG3 is a meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I.
仅用于科研。不用于诊断过程。未经明确授权不得转售。