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Invitrogen
STK38 Polyclonal Antibody
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STK38 Antibody (PA5-72119) in WB
Western blot analysis of Mouse Stk38 in mouse liver lysate using 20 µg of protein per lane. Samples were first blocked with 5% NFDM/TBST, incubated with Mouse Stk38 polyclonal antibody (Product # PA5-72119) using a dilution of 1:1000 followed by a goat anti-rabbit IgG H&L (HRP) secondary antibody with a dilution of 1:10,000.
产品信息
PA5-72119
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 429-458 amino acids from the C-terminal region of mouse Stk38
偶联物
形式
Liquid
浓度
0.5 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
靶标信息
STK38 (also known as NDR) or Nuclear Dbf2-related protein is a serine/threonine kinase in the subgroup of the AGC kinase family that is regulated by Mob proteins. Fas and TNFα receptor stimulation activates human STK38 by promoting phosphorylation at the hydrophobic motif. NDR acts as a novel pro-apoptotic kinase, and is a key member of the RASSF1A/MST1 signaling cascade. STK38 is crucial for the fidelity of mitotic chromosome alignment in mammalian cells. STK38 is incorporated into the HIV-1 particles and is cleaved by the HIV-1 protease. STK38-driven centrosome duplication requires Cdk2 activity, and Cdk2-induced centrosome amplification is affected upon reduction of STK38 activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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