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Invitrogen
STOX1 Polyclonal Antibody
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产品信息
PA5-65193
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: DESRLMPASMT YLVSMESCAE SAQENAAPIS HCQSCQCFRD MHTQDVQEAP VAAEVTRKSH RGLGESVSWV QNGAVSVSAE HH
Highest antigen sequence identity to the following orthologs - mouse 47%, rat 43%.
靶标信息
STOX1 (Storkhead box 1), also known as PEE4 or C10orf24, is a winged-helix domain containing transcription factor believed to play a role in the differentiation of stem cells. As a DNA-binding protein, STOX1 exists as three alternatively spliced isoforms, designated A, B and C, all of which localize to either the cytoplasm or the nucleus. Defects in STOX1 are the cause of pre-eclampsia/eclampsia 4 (PEE4), also known as gestational proteinuric hypertension. STOX1 was also found to be functionally involved in late-onset Alzheimer's disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: PEE4; Storkhead-box protein 1; Winged-helix domain-containing protein
基因别名: C10orf24; STOX1
UniProt ID: (Human) Q6ZVD7
Entrez Gene ID: (Human) 219736
transcription, DNA-templated
mitotic nuclear division
positive regulation of cell proliferation
regulation of gene expression
positive regulation of gene expression
negative regulation of gene expression
positive regulation of peptidyl-threonine phosphorylation
regulation of mitochondrion organization
positive regulation of G2/M transition of mitotic cell cycle
positive regulation of peptidyl-serine phosphorylation
inner ear development
positive regulation of epithelial cell proliferation
cell division
regulation of mitochondrial membrane potential
positive regulation of protein kinase B signaling
regulation of transcription from RNA polymerase II promoter in response to hypoxia
cellular response to nitrosative stress
regulation of mitochondrial DNA metabolic process
regulation of response to oxidative stress
positive regulation of cyclin-dependent protein kinase activity
positive regulation of otic vesicle morphogenesis
